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* Correspondence
Bold: Equally contributed

2023年（令和5年）

  • Mitaka T*, Ichinohe N, Tanimizu N.”Small Hepatocytes” in the Liver. Cells 2023 Nov 27; 12(23):2718. doi.org/10.3390/cells12232718
  • Tanimizu N*, Ichinohe N, Mitaka T.　β-adrenergic receptor agonist promotes ductular expansion during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury. Scientific Reports 2023 May 1;13(1):7084. doi: 10.1038/s41598-023-33882-w
  • Ichinohe N*, Tanimizu N, Ishigami K, Yoshioka Y, Fujitani N, Ochiya T, Takahashi M, Mitaka T*. CINC-2 and miR-199a-5p in EVs secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration. Stem Cell Research & Therapy, 2023 14:134 https://doi.org/10.1186/s13287-023-03346-z

2021年（令和3年）

  • Tanimizu N*, Ichinohe N, Sasaki Y, Itoh T, Sudo R, Yamaguchi T, Katsuda T, Ninomiya T, Tokino T, Ochiya T, Miyajima A, Mitaka T. Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo. Nature Communications 2021 Jun 07; 12:3390  doi: 10.1038/s41467-021-23575-1
  • Ichinohe N*, Ishii M, Tanimizu N, Mizuguchi T, Yoshioka Y, Ochiya T, Suzuki H, Mitaka T*. Extracellular vesicles containing miR-146a-5p secreted by bone marrow mesenchymal cells activate hepatocytic progenitors in regenerating rat livers. Stem Cell Research & Therapy 2021 May 29;12(1):312 doi: 10.1186/s13287-021-02387-6
  • Tanimizu N*. The neonatal liver: Normal development and response to injury and disease. Seminars in Fetal and Neonatal Medicine 2021 Mar 17:101229 doi: 10.1016/j.siny.2021.101229

2020年（令和2年）

  • Tanimizu N*, Ichinohe N, Suzuki H, Mitaka T. Increased oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice. Aging-US, 2020 Oct 1;12.　doi: 10.18632/aging.103973
  • Kino J, Ichinohe N, Ishii M, Suzuki H, Mizuguchi T, Tanimizu N, Mitaka T*. Self‐Renewal Capability of Hepatocytic Parental Progenitor Cells Derived From Adult Rat Liver Is Maintained Long Term When Cultured on Laminin 111 in Serum‐Free Medium. Hepatology Communications, 2019 Nov 2;4(1):21-37. doi: 1002/hep4.1442. eCollection 2020 Jan

2019年（平成31年）

  • Kino J, Ichinohe N, Ishii M, Mitaka T*. Isolation and expansion of rat hepatocytic progenitor cells. Methods Mol Biol,  1905: 29-41 (2019)  doi: 10.1007/978-1-4939-8961-4_4

  • Tanimiu N*. Isolation of bipotential liver progenitor cells from neonatal mouse liver. Methods Mol Biol, 1905: 9-17 (2019) doi: 10.1007/978-1-4939-8961-4_2

  • Tanimizu N*. Identification and in vitro expansion of adult hepatocyte progenitors from chronically injured liver. Methods Mol Biol, 1940:267-273(2019) doi: 10.1007/978-1-4939-9086-3_19

2018年（平成30年)

  • Tanimizu N*, Ichinohe N, Mitaka T. Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver. Development, Apr 25;145(9). pii: dev159095 (2018) doi: 10.1242/dev.159095

2017年（平成29年）

  • Ishii M, Kino J, Ichinohe N, Tanimizu N, Ninomiya T, Suzuki H, Mizuguchi T, Hirata K, Mitaka T*. Hepatocytic parental progenitor cells of rat small hepatocytes maintain a self-renewal capability after long-term culture. Sci Rep, Apr 11; 7: 46177 (2017) DOI: 10.1038/srep46177
  • Tanimizu N*, Mitaka T. Epithelial morphogenesis during liver development. Cold Spring Harb Perspect Biol, Feb 17; pil: a027862 (2017). doi: 10.1101/cshperspect.a027862
  • Tanimizu N*, Mitaka T. Which is better source for functional hepatocytes? (Editorial) Stem Cell Invest, Feb 16; 4:12 (2017) doi: 10.21037/sci.2017.02.08
  • Ichinohe N*, Ishii M, Tanimizu N, Kon J, Mizuguchi T, Hirata K, Mitaka T*. Transplantation of galactosamine-induced hepatic Thy1-positive cells activates the growth of intrinsic hepatic progenitor cells in retrorsine-treated rat livers. Stem Cells, 35(4): 920-931 (2017) doi: 10.1002/stem.2548
  • Tanimizu N*, Ichinohe N, Yamamoto M, Akiyama H, Nishikawa Y, Mitaka T. Progressive induction of liver progenitor cells in chronically injured liver. Sci Rep, Jan 4; 7: 39990 (2017) doi: 10.1038/srep39990

2016年（平成28年）

  • Tanimizu N*, Ichinohe N, Ishii M, Kino J, Mizuguchi T, Hirata K, Mitaka T. Liver progenitors isolated from adult healthy mouse liver efficiently differentiate to functional hepatocytes in vitro and repopulate liver tissue. Stem Cells, 34(12): 2889-2901 (2016) doi: 10.1002/stem.2457
  • Tanimizu N*, Kaneko K, Itoh T, Ichinohe N, Ishii M, Mizuguchi T, Hirata K, Miyajima A, Mitaka T. Intrahepatic bile ducts are developed through formation of homogeneous continuous luminal network and its dynamic rearrangement. Hepatology, 64(1): 175-188 (2016) doi: 10.1002/hep.28521
  • Tanimizu N*, Mitaka T (Review). Morphogenesis of Liver Epithelial Cells. Hepatol Res, 46(10): 964-976 (2016) doi: 10.1111/hepr.12654
  • Okita K, Mizuguchi T, Ota S, Ishi M, Nishidate T, Ueki T, Meguro M, Kimura Y, Tanimizu N, Ichinohe N, Torigoe T, Kojima T, Mitaka T, Sato N, Sawada N, Hirata K (Review). Pancreatic regeneration: basic research and gene regulation. Surg Today, 46(6): 633-640 (2016) doi: 10.1007/s00595-015-1215-2.

2015年（平成27年）

  • Tanimizu N*. Clonal culture of mouse liver progenitor cells. Bioprotocol, 5: 1-7 (2015)
  • Kasuya J*, Sudo R, Masuda G, Mitaka T, Ikeda M, Tanishita K. Reconstruction of hepatic stellate cell-incorporated liver sinusoidal structures in small hepatocyte tri-culture using microporous membranes. J Tissue Eng Regen Med (JTERM), 9(3): 247-256 (2015) doi: 10.1002/term.1630

2014年（平成26年）

  • Tanimizu N*, Kobayashi S, Ichinohe N, Mitaka T. Downregulation of miR122 by grainyhead like-2 restricts the hepatocytic differentiation potential of adult liver progenitor cells. Development, 141(23): 4448-4456 (2014) doi: 10.1242/dev.113654
  • Kikkawa Y*, Miwa T, Tanimizu N, Kadoya Y, Ogawa T, Katagiri F, Hozumi K, Nomizu M, Mizuguchi T, Hirata K, Mitaka T. Soluble lutheran/basal cell adhesion molecule is detectable in plasma of hepatocellular carcinoma patients and modulates cellular interaction with laminin-511 in vitro. Exp Cell Res, 328(1): 197-206 (2014) doi: 10.1016/j.yexcr.2014.07.012
  • Nakamura Y, Mizuguchi T*, Tanimizu N, Ooe H, Ichinohe N, Hirata K, Mitaka T. Preoperative hepatocyte transplantation prevents cirrhotic rats from receiving the fatal damage by a liver resection. Cell Transplantation, 23(10): 1243-1254 (2014) doi: 10.3727/096368913X668645
  • Tanimizu N*, Nishikawa Y, Ichinohe N, Akiyama H, Mitaka T. Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes areinvolved in mouse liver regeneration. J Biol Chem, 289(11): 7589-7598 (2014) doi: 10.1074/jbc.M113.517243
  • Takeda H*. Effects of Cd2+ on cis-dimer structure of E-cadherin in living cells. Biochem Biophys Res Commun, Feb 21; 444(4): 467-472 (2014) doi: 10.1016/j.bbrc.2014.01.072
  • Tanimizu N*, Mitaka T (Review). Reevaluation of cell supply from liver stem/progenitor cells and the lineage conversion during liver development and regeneration. Organogenesis, 10(2): 208-215 (2014) doi: 10.4161/org.27591

2013年（平成25年）

  • Tanimizu N*, Nakamura Y, Ichinohe N, Mizuguchi T, Hirata K, Mitaka T. Hepatic biliary epithelial cells acquire epithelial integrity but lose plasticity to differentiate into hepatocytes in vitro during development. J Cell Sci, 126(22): 5239-5246 (2013) doi: 10.1242/jcs.133082
  • Kiyohashi K, Kakinuma S*, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fijuki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M. Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells. Hepatology, 57(6): 2502-2513 (2013) doi: 10.1002/hep.26293
  • Tanimizu N*, Mitaka T (Review). Role of Grainyhead-like 2 in the formation of functional tight junctions. Tissue Barriers, Commentaries, 1:e23495 (2013) doi: 10.4161/tisb.23495
  • Kalchman J, Fujioka S, Chung S, Kikkawa Y, Mitaka T, Kamm RD, Tanishita K, Sudo R*. A three-dimensional microfluidic cancer cell migration assay to screen the effect of anti-migratory drugs and interstitial flow. Microfluidics and Nanofluidics, 14(6): 969-981 (2013) doi: https://doi.org/10.1007/s10404-012-1104-6
  • Ichinohe N*, Tanimizu N, Ooe H, Nakamura Y, Mizuguchi T, Hirata K, Kon J, Mitaka T*. Differentiation capacity of hepatic stem/progenitor cells isolated from d-galactosamine-treated rat livers. Hepatology, 57(3): 1192-1202 (2013) doi: 10.1002/hep.26084
  • 三高俊広　（総説）．肝細胞．　Surgery Frontier, 20(1), 74-76 (2013)

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